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Route/Dosage. PO (Adults): Hypertension: 10 mg 4 times daily initially. After 2-4 days may ↑ to 25 mg 4 times daily for the rest of the 1st wk; may then ↑ to 50 mg 4 times daily (up to 300 mg/day). Once maintenance dose is established, twice-daily dosing may be used. HF: 25-37.5 mg 4 times daily; may be ↑ up to 300 mg/day in 3-4 ...Implementation. IV Administration. 1 - 19 of 19 records. normal saline was found in Davis's Drug Guide. Davis's Drug Guide for Nurses App + Web from F.A. Davis and Unbound Medicine covers 5000+ trade name and generic drugs. Includes App for iPhone, iPad, and Android smartphone + tablet. Handbook covers dosage, side effects, interactions, uses.

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